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By Ian Stuart-Hamilton

With the world's inhabitants getting more and more older, there hasn't ever been a extra urgent desire for the learn of previous age and growing older. An creation to Gerontology presents a wide-ranging creation to this significant subject. by means of assuming no previous professional wisdom and averting jargon, this publication will advisor scholars via the entire major topics in gerontology, overlaying either conventional parts, equivalent to organic and social ageing, in addition to extra modern components, akin to expertise, the humanities, sexuality and schooling of older adults. An creation to Gerontology is written through a crew of foreign authors with multidisciplinary backgrounds who draw facts from quite a few various views and traditions.

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Initially, it was thought that increasing the concentration of GH at older ages would restore youthfulness. In reality, this is not the case and mice with high levels of GH tend to have shorter lifespans and maybe even age faster (Bartke, 2003). As discussed above, the results from CR and genetic mutations suggest that an attenuation of the GH/IGF1 axis increases lifespan. , 2001; de Magalh˜aes, 2005; Masoro, 2005). Therefore, hormones appear to play some role in the ageing process. However, it is not clear yet how widespread this role is and which downstream mechanisms are involved.

2005), and the idea that mutations to mitochondrial DNA contribute to ageing and age-related diseases remains a powerful one (Wallace, 1992). Cellular senescence and organismal ageing In 1961, and contradicting what was thought at the time, Leonard Hayflick and Paul Moorhead discovered that human cells can only divide a finite number of times in culture (Hayflick and Moorhead, 1961). Because studying cells in vitro is easier than studying animals or humans, this phenomenon, termed replicative senescence (RS), has been intensively studied for decades.

Introduction Larson, R. (1978) Thirty years of research on the subjective well-being of older Americans, Journal of Gerontology, 33, 109–25. , Ezzati, M. et al. (2006) Global burden of disease and risk factors. Washington, DC: World Bank/Oxford University Press. J. et al. (2008) Socioeconomic inequalities in morbidity and mortality in Western Europe, New England Journal of Medicine, 358, 2468–81. I. (1970a) Persistence of life style among the elderly, in E. ), Normal aging. Durham, NC: Duke University Press, 329–31.

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An Introduction to Gerontology by Ian Stuart-Hamilton


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