By Lori A. Erickson
Atlas of Endocrine Pathology presents a entire compendium of photomicrographs of universal and unusual entities in endocrine pathology. the amount contains histologic beneficial properties of ordinary positive aspects, reactive stipulations, hyperplasia, and tumors. the main worthwhile diagnostic gains are illustrated to supply path and clues to the analysis of endocrine tumors. moreover, photomicrographs spotlight the main pertinent diagnostic gains in frustrating diagnoses in endocrine pathology.
Authored by means of a nationally and the world over well-known pathologist, Atlas of Endocrine Pathology is a vital studying device for these turning into conversant in the various entities encountered in endocrine pathology and a necessary reference for training pathologists confronted with hard diagnoses in endocrine pathology.
Table of Contents
1 Thyroid Histology
3 Graves ailment (Diffuse Hyperplasia)
4 Thyroid Goiter
5 Papillary Thyroid Carcinoma
6 Hyalinizing Trabecular Tumor
7 Follicular Thyroid Neoplasms
8 Hurthle phone Thyroid Neoplasms
9 Poorly Differentiated Thyroid Carcinoma
10 Anaplastic Thyroid Carcinoma
11 Tumors of C Cells
12 strange Thyroid Tumors
13 Metastases to Thyroid
14 Parathyroid Histology
15 Parathyroid Hyperplasia
16 Parathyroid Adenoma
17 Parathyroid Carcinoma
19 Metastases to Parathyroid
20 Adrenal Gland Histology
21 Adrenal Cysts
22 Adrenal Cortical Hyperplasia
23 Adrenal Cortical Adenoma
24 Adrenal Cortical Carcinoma
25 Adrenal Myelolipoma
26 Pheochromocytoma and Adrenal Medullary Hyperplasia
27 Ganglioneuroma and Neuroblastoma
28 strange Adrenal Tumors
29 Metastases to the Adrenal Gland
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Additional info for Atlas of Endocrine Pathology (Atlas of Anatomic Pathology)
2013;42(1):77–8. 19 11. Dimos G, Pappas G, Akritidis N. Subacute thyroiditis in the course of novel H1N1 influenza infection. Endocrine. 2010;37(3): 440–1. 12. Volpe R. Subacute thyroiditis. Prog Clin Biol Res. 1981;74:115–34. 13. Volpe R. The pathology of thyroiditis. Hum Pathol. 1978; 9(4):429–38. 14. Few J, et al. Riedel’s thyroiditis: treatment with tamoxifen. Surgery. 1996;120(6):993–8; discussion 998–9. 15. Heufelder AE, Hay ID. Further evidence for autoimmune mechanisms in the pathogenesis of Riedel’s invasive fibrous thyroiditis.
The diffuse sclerosing variant of PTC has prominent calcifications, numerous psammoma bodies, fibrosis, squamous metaplasia, and a marked lymphocytic infiltrate. This variant, described in 1985, is more common in females and young patients . This tumor often has aggressive features of large size, diffuse involvement of both lobes, prominent angiolymphatic invasion throughout the thyroid, and increased lymph node and lung metastases [46, 47]. Ultrastructurally, the dissemination in the thyroid is the result of lymphatic invasion .
34 Follicular variant of papillary thyroid carcinoma. HBME-1 shows membranous and some cytoplasmic staining of the tumor cells in this FVPTC. The colloid also shows staining, but this is not specific. Several immunohistochemical markers, such as HBME-1, galectin-3, CITED-1, and keratin 19, may be helpful in confirming a diagnosis of FVPTC . Although a panel of immunostains may be most helpful, HBME-1 is probably the best single marker to assist in differentiating FVPTC from a follicular neoplasm or adenomatous nodule Fig.
Atlas of Endocrine Pathology (Atlas of Anatomic Pathology) by Lori A. Erickson